منابع مشابه
Structure of Mycobacterium leprae.
Introduction : why study structure? Information about the structure of M. leprae may be obtained by microscopy (especially electron miscroscopy) and other physical techniques . There is active development of such techniques , but at present the information they can give about structures as complex as a bac terium is l imited . To obtain a detailed knowledge of the molecular composition and con...
متن کاملAdjuvant activity of Mycobacterium leprae.
Mycobacterium leprae organisms isolated from infected spleen and liver tissue by zonal centrifugation were shown to possess adjuvant activity. Histochemical examination of the footpad macrophage epithelioid granuloma showed that macrophages contained large amounts of hemosiderin after the injection of M. leprae and much smaller amounts after the injection of M. tuberculosis.
متن کاملMycobacterium leprae. A multifactorial approach
Evidence is accumulating that Mycobacterium leprae is probably a microbe dependent microbe. l O1 3 The first report that multiplication of M. leprae was promoted by a growth factor of mycobacterial origin was proposed by Twort l 9 in 1 9 1 0 , two years before the discovery of the cultivation of 'lohne's bacilli' in media enriched with heat-killed mycobacteria . 2o The growth factor was identi...
متن کاملA Mycobacterium leprae VNTR database.
A great deal of the last quarter of a century’s astonishing progress in understanding and treating human disease is attributable to the existence of public databases where information about DNA sequences, protein sequences, protein structures, human variation, etc. is stored and is freely available to all interested investigators. Information that is developed by one laboratory to help answer a...
متن کاملDNA metabolism in Mycobacterium leprae.
Understanding the molecular basis underlying the hallmark features of Mycobacterium leprae, such as its parasitism and extraordinarily slow growth rate, has stimulated research into the biology of this pathogen for decades, but it is through the completion of its genome sequence that a quantum leap of progress has been achieved. 1 ln this review, we analyse the genes in M. leprae that are invol...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 1983
ISSN: 0305-7518
DOI: 10.5935/0305-7518.19830045